小鼠抗MRPS34单克隆抗体

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternate splice variants of this gene have been described but their full-length nature has not been determined. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Applications:

WB, IHC, IF

Name of antibody:

MRPS34

Immunogen:

Fusion protein of human MRPS34

Full name:

mitochondrial ribosomal protein S34 (MRPS34), transcript variant 2

Synonyms:

MRP-S12; MRP-S34; MRPS12

SwissProt:

P82930

IHC positive control:

carcinoma of human thyroid tissue and human bladder tissue; human colon tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

26 kDa

WB Positive control:

Hela, MDCK cell lysates

WB Recommended dilution:

200-1000