小鼠抗MAPK3单克隆抗体

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq].

Applications:

WB, IHC, IF

Name of antibody:

MAPK3

Immunogen:

Fusion protein of human MAPK3

Full name:

mitogen-activated protein kinase 3 (MAPK3), transcript variant 1

Synonyms:

ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK

SwissProt:

P27361

IHC positive control:

adenocarcinoma of human ovary tissue and human pancreas tissue; adenocarcinoma of human endometrium tissue and human tonsil tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

43 kDa

WB Positive control:

HepG2, Hela, A549, COS7, Jurkat, MDCK, MCF-7 cell lysates

WB Recommended dilution:

500-2000