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Fusion protein corresponding to a region derived from 30-406 amino acids of human ERP44 |
技术规格
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Full name: |
endoplasmic reticulum protein 44 |
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Synonyms: |
PDIA10; TXNDC4 |
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Swissprot: |
Q9BS26 |
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Gene Accession: |
BC005374 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum. |
