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  • TNNI3 抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW5697
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: TNNI3 抗原(重组蛋白)

英文名称:
TNNI3 Antigen (Recombinant Protein)

别      名 CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF

相关类别:抗原

储      存: 冷冻(-20℃)

概      述

Fusion protein corresponding to a region derived from 44-210 amino acids of human TNNI3

技术规格

Full name:

troponin I type 3 (cardiac)

Synonyms:

CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF

Swissprot:

P19429

Gene Accession:

BC096165

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).