兔抗CDC25C(Phospho-Ser198)多克隆抗体

Background:

This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008]

Applications:

IHC

Name of antibody:

CDC25C(Phospho-Ser198)

Immunogen:

Peptide sequence around phosphorylation site of Serine 198(E-F-S(p)-L-K) derived from Human CDC25C.

Full name:

cell division cycle 25C

Synonyms：

CDC25; PPP1R60

SwissProt:

P30307

IHC positive control:

Human colon carcinoma tissue

IHC Recommend dilution:

50-100