兔抗CCNE1(Ab-395)多克隆抗体

Background:

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.

Applications:

WB, IHC, IF

Name of antibody:

CCNE1(Ab-395)

Immunogen:

Synthesized non-phosphopeptide derived from human Cyclin E1 around the phosphorylation site of threonine 395 (L-L-T-P-P).

Full name:

cyclin E1

Synonyms：

CCNE

SwissProt:

P24864

IHC positive control:

Human colon carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

47 kDa

WB Positive control:

Hela cells treated with Paclitasel (1uM, 60mins) lysate

WB Recommended dilution:

500-3000

IF positive control:

Huvec cells

IF Recommend dilution:

100-500