兔抗CCL2多克隆抗体

Background:

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Applications:

ELISA, IHC

Name of antibody:

CCL2

Immunogen:

Synthetic peptide of human CCL2

Full name:

C-C motif chemokine 2

Synonyms：

HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30

SwissProt:

P13500

ELISA Recommended dilution:

500-5000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

25-50