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中文名称：兔抗CARD16多克隆抗体
英文名称： Anti-CARD16 rabbit polyclonal antibody
别 名： caspase recruitment domain family member 16; COP; COP1; PSEUDO-ICE
克隆类型： rabbit polyclonal
技术规格
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Background: |
Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
CARD16 |
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Immunogen: |
Synthetic peptide of human CARD16 |
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Full name: |
caspase recruitment domain family member 16 |
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Synonyms: |
COP; COP1; PSEUDO-ICE |
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SwissProt: |
Q5EG05 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
40-200 |
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WB Predicted band size: |
23 kDa |
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WB Positive control: |
Human placenta tissue lysate |
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WB Recommended dilution: |
500-2000 |
