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中文名称： CD86 抗原（重组蛋白）
英文名称：CD86 Antigen (Recombinant Protein)
储 存： 冷冻（-20℃）
概 述
技术规格
|
Full name: |
CD86 molecule |
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Synonyms: |
B70; B7-2; B7.2; LAB72; CD28LG2 |
|
Swissprot: |
P42081 |
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Gene Accession: |
BC040261 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
