兔抗ATP7B 多克隆抗体

Background:

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Applications:

ELISA, IHC

Name of antibody:

ATP7B

Immunogen:

Synthetic peptide of human ATP7B

Full name:

ATPase, Cu++ transporting, beta polypeptide

Synonyms：

WD; PWD; WC1; WND

SwissProt:

P35670

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human esophagus cancer

IHC Recommend dilution:

25-100