兔抗ASPSCR1多克隆抗体

Background:

The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

Applications:

ELISA, IHC

Name of antibody:

ASPSCR1

Immunogen:

Fusion protein of human ASPSCR1

Full name:

ASPSCR1 tether for SLC2A4, UBX domain containing

Synonyms:

TUG; ASPL; ASPS; RCC17; UBXD9; UBXN9; ASPCR1

SwissProt:

Q9BZE9

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

50-100