兔抗SPAG4多克隆抗体

Background:

The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail. Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility. In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, WB, IHC

Name of antibody:

SPAG4

Immunogen:

Synthetic peptide of human SPAG4

Full name:

sperm associated antigen 4

Synonyms:

SUN4; CT127

SwissProt:

Q9NPE6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer and Human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

48 kDa

WB Positive control:

Human bladder transitional cell carcinoma grade 2-3 tissue lysate

WB Recommended dilution:

200-1000