兔抗FGFR1OP多克隆抗体

Background:

This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.

Applications:

ELISA, IHC

Name of antibody:

FGFR1OP

Immunogen:

Fusion protein of human FGFR1OP

Full name:

FGFR1 oncogene partner

Synonyms：

FOP

SwissProt:

O95684

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human colon cancer and human cervical cancer

IHC Recommend dilution:

100-300