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Background: |
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FAAP24 |
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Immunogen: |
Synthetic peptide of human FAAP24 |
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Full name: |
Fanconi anemia core complex associated protein 24 |
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Synonyms: |
C19orf40 |
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SwissProt: |
Q9BTP7 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer and Human lung cancer |
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IHC Recommend dilution: |
30-150 |

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