中文名称:LDB1抗原(重组蛋白)
英文名称: LDB1 Antigen (Recombinant Protein)
别 名: NLI; CLIM2; LDB-1; CLIM-2
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to a region derived from 212-411 amino acids of human LDB1 | 
| Full name: | LIM domain binding 1 | 
| Synonyms: | NLI; CLIM2; LDB-1; CLIM-2 | 
| Swissprot: | Q86U70 | 
| Gene Accession: | BC000482 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity). | 
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