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中文名称：PPM1B抗原（重组蛋白）
英文名称 PPM1B Antigen (Recombinant Protein)
别 名： PP2CB; PP2CBETA; PP2C-beta; PPC2BETAX; PP2C-beta-X
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 288-479 amino acids of human PPM1B |
技术规格：
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Full name: |
protein phosphatase, Mg2+/Mn2+ dependent 1B |
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Synonyms: |
PP2CB; PP2CBETA; PP2C-beta; PPC2BETAX; PP2C-beta-X |
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Swissprot: |
O75688 |
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Gene Accession: |
BC012002 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. |
