中文名称: ZBTB44 抗原(重组蛋白)
英文名称: ZBTB44 Antigen (Recombinant Protein)
别 名: zinc finger and BTB domain containing 44; BTBD15; ZNF851; HSPC063
相关类别:抗原
储 存: 冷冻(-20℃)
概 述
| Full name: | zinc finger and BTB domain containing 44 | 
| Synonyms: | BTBD15; ZNF851; HSPC063 | 
| Swissprot: | Q8NCP5 | 
| Gene Accession: | BC030580 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 44 (ZBTB44), also known as BTBD15, is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified. | 
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