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  • IL18R1抗原(重组蛋白)

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    • 目录号 : TW17943
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中文名称:IL18R1抗原(重组蛋白)

英文名称: IL18R1 Antigen (Recombinant Protein)

储      存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 75-329 amino acids of human IL18R1


技术规格

Full name:

interleukin 18 receptor 1

Synonyms:

CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp

Swissprot:

Q13478

Gene Accession:

BC069575

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.