兔抗DDX11多克隆抗体

Background:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Applications:

ELISA, IHC

Name of antibody:

DDX11

Immunogen:

Fusion protein of human DDX11

Full name:

DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11

Synonyms：

CHL1; KRG2; WABS; CHLR1

SwissProt:

Q96FC9

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human ovarian cancer and Human breast cancer

IHC Recommend dilution:

50-200