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021-54845833/15800441009
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Full name: |
nuclear receptor subfamily 1, group D, member 1 |
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Synonyms: |
EAR1; hRev; THRA1; THRAL; ear-1 |
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Swissprot: |
P20393 |
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Gene Accession: |
BC047875 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. |
