中文名称:TAX1BP1 抗原(重组蛋白)
英文名称: TAX1BP1 Antigen (Recombinant Protein)
别 名: Tax1 (human T-cell leukemia virus type I) binding protein 1; T6BP; TXBP151; CALCOCO3
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to a region derived from 180-420 amino acids of human TAX1BP1 | 
| Full name: | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 
| Synonyms: | T6BP; TXBP151; CALCOCO3 | 
| Swissprot: | Q86VP1 | 
| Gene Accession: | BC050358 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[ | 
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