中文名称: LTA4H 抗原(重组蛋白)
英文名称: LTA4H Antigen (Recombinant Protein)
储 存: 冷冻(-20℃)
别 名: leukotriene A4 hydrolase
相关类别: 抗原
概 述
| Fusion protein corresponding to a region derived from 251-511 amino acids of human LTA4H | 
| Full name: | leukotriene A4 hydrolase | 
| Swissprot: | P09960 | 
| Gene Accession: | BC032528 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | LTA4H (Leukotriene A4-hydrolase ) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein. | 
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