PPIB抗原（重组蛋白）

Full name:

peptidylprolyl isomerase B (cyclophilin B)

Synonyms:

OI9; CYPB; SCYLP; CYP-S1

Swissprot:

P23284

Gene Accession:

BC001125

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.