兔抗CYP46A1多克隆抗体

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Applications:

ELISA, WB, IHC

Name of antibody:

CYP46A1

Immunogen:

Synthetic peptide of human CYP46A1

Full name:

cytochrome P450, family 46, subfamily A, polypeptide 1

Synonyms：

CP46; CYP46

SwissProt:

Q9Y6A2

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human brain and Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

57 kDa

WB Positive control:

Human lymphoma tissue

WB Recommended dilution:

200-1000