购物车
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中文名称： AKR1C4 抗原（重组蛋白）
技术规格
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Full name: |
aldo-keto reductase family 1, member C4 |
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Synonyms: |
C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD |
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Swissprot: |
P17516 |
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Gene Accession: |
BC020744 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |
