MAP4K3抗原（重组蛋白）

Full name:

Mitogen-activated protein kinase kinase kinase kinase 3

Synonyms:

GLK; MEKKK3; MEKKK 3; MAPKKKK3; RAB8IPL1

Swissprot:

Q8IVH8

Gene Accession:

BC071579

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.