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中文名称：APLF 抗原（重组蛋白）
英文名称： APLF Antigen (Recombinant Protein)
别 名： aprataxin and PNKP like factor; APFL; PALF; Xip1; C2orf13
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human APLF |
|
Full name: |
aprataxin and PNKP like factor |
|
Synonyms: |
APFL; PALF; Xip1; C2orf13 |
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Swissprot: |
Q8IW19 |
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Gene Accession: |
BC041144 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. |
