兔抗AKR1C2多克隆抗体

Background:

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

AKR1C2

Immunogen:

Synthesized peptide derived from internal of human AKR1C2.

Full name:

aldo-keto reductase family 1, member C2

Synonyms：

DD; DD2; TDD; BABP; DDH2; HBAB; HAKRD; MCDR2; SRXY8; AKR1C-pseudo

SwissProt:

P52895

WB Predicted band size:

37 kDa

WB Positive control:

COLO cells lysate

WB Recommended dilution:

500-3000