兔抗GFI1B多克隆抗体

Background:

This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

GFI1B

Immunogen:

Synthetic peptide of human GFI1B

Full name:

growth factor independent 1B transcriptional repressor

Synonyms:

BDPLT17; ZNF163B

SwissProt:

Q5VTD9

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

50-300