兔抗CKMT2多克隆抗体

Background:

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

CKMT2

Immunogen:

Fusion protein of human CKMT2

Full name:

creatine kinase, mitochondrial 2 (sarcomeric)

Synonyms：

SMTCK

SwissProt:

P17540

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain and human thyroid cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

48 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

500-2000