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021-54845833/15800441009
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Fusion protein corresponding to a region derived from 194-393 amino acids of human HENMT1 |
技术规格
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Full name: |
HEN1 methyltransferase homolog 1 |
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Synonyms: |
HEN1; C1orf59 |
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Swissprot: |
Q5T8I9 |
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Gene Accession: |
BC012198 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis. |
