兔抗KLK7多克隆抗体

Background:

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.

Applications:

ELISA, IHC

Name of antibody:

KLK7

Immunogen:

Fusion protein of human KLK7

Full name:

kallikrein-related peptidase 7

Synonyms：

hK7, SCCE, PRSS6

SwissProt:

P49862

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer and human ovarian cancer

IHC Recommend dilution:

25-100