小鼠抗EPCAM单克隆抗体

Background:

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008].

Applications:

WB, IHC, IF, FC

Name of antibody:

EPCAM

Immunogen:

Fusion protein of human EPCAM

Full name:

epithelial cell adhesion molecule (EPCAM)

Synonyms:

DIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1

SwissProt:

P16422

IHC positive control:

adenocarcinoma of human ovary tissue and carcinoma of human pancreas tissue

IHC Recommend dilution:

100-500

WB Predicted band size:

35 kDa

WB Positive control:

HepG2, MDCK, MCF-7 cell lysates

WB Recommended dilution:

500-2000