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中文名称： UBE4A 抗原（重组蛋白）
英文名称： UBE4A Antigen (Recombinant Protein)
别 名： ubiquitination factor E4A; E4; UFD2; UBOX2
相关类别：抗原
储 存： 冷冻（-20℃）
概 述
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Full name: |
ubiquitination factor E4A |
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Synonyms: |
E4; UFD2; UBOX2 |
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Swissprot: |
Q14139 |
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Gene Accession: |
BC112367 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
