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中文名称： TYK2 抗原（重组蛋白）
英文名称： TYK2 Antigen (Recombinant Protein)
别 名： tyrosine kinase 2; JTK1; IMD35
储 存： 冷冻（-20℃）
相关类别：抗原
概 述
|
Full name: |
tyrosine kinase 2 |
|
Synonyms: |
JTK1; IMD35 |
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Swissprot: |
P29597 |
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Gene Accession: |
BC014243 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. |
