SERPINB2 抗原（重组蛋白）

Full name:

serpin peptidase inhibitor, clade B (ovalbumin), member 2

Synonyms:

PAI; PAI2; PAI-2; PLANH2; HsT1201

Swissprot:

P05120

Gene Accession:

BC012609

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor that inactivates tPA and urokinase. It is present in most cells, especiallymonocytes/macrophages. PAI-2 exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy.