DHCR24 抗原（重组蛋白）

Full name:

24-dehydrocholesterol reductase

Synonyms:

DCE; SELADIN1; Nbla03646; seladin-1

Swissprot:

Q15392

Gene Accession:

BC004375

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis.