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中文名称： CIAO2A 抗原（重组蛋白）
英文名称：CIAO2A Antigen (Recombinant Protein)
别 名： cytosolic iron-sulfur assembly component 2A; CIA2A; FAM96A
相关类别：抗原
储 存： 冷冻（-20℃）
概 述
技术规格
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Full name: |
cytosolic iron-sulfur assembly component 2A |
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Synonyms: |
CIA2A; FAM96A |
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Swissprot: |
Q9H5X1 |
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Gene Accession: |
BC008865 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). |
