兔抗APPL1多克隆抗体

Background:

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Applications:

ELISA, WB, IHC

Name of antibody:

APPL1

Immunogen:

Fusion protein of human APPL1

Full name:

Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

Synonyms：

APPL; DIP13alpha

SwissProt:

Q9UKG1

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and human lung cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

80 kDa

WB Positive control:

A172 cells

WB Recommended dilution:

500-2000