兔抗SH2B2多克隆抗体

Background:

The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Applications:

ELISA, IHC

Name of antibody:

SH2B2

Immunogen:

Synthetic peptide of human SH2B2

Full name:

SH2B adaptor protein 2

Synonyms：

APS

SwissProt:

O14492

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human gastric cancer

IHC Recommend dilution:

15-50