兔抗NLRP7多克隆抗体

Background:

This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

NLRP7

Immunogen:

Synthetic peptide of human NLRP7

Full name:

NLR family, pyrin domain containing 7

Synonyms:

HYDM; PAN7; NALP7; NOD12; PYPAF3; CLR19.4

SwissProt:

Q8WX94

IHC positive control:

Human gastric cancer and human brain

IHC Recommend dilution:

100-300