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概 述
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Full name: |
tumor necrosis factor, alpha-induced protein 8 |
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Synonyms: |
NDED; GG2-1; SCCS2; SCC-S2; MDC-3.13 |
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Swissprot: |
O95379 |
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Gene Accession: |
BC007014 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. |
