兔抗DSC2多克隆抗体

Background:

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.

Applications:

ELISA, IHC

Name of antibody:

DSC2

Immunogen:

Synthetic peptide of human DSC2

Full name:

desmocollin 2

Synonyms:

DG2; DSC3; CDHF2; ARVD11; DGII/III

SwissProt:

Q02487

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

25-100