中文名称:GMDS抗原(重组蛋白)
英文名称: GMDS Antigen (Recombinant Protein)
别 名: GMD; SDR3E1
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to a region derived from 173-372 amino acids of human GMDS | 
| Full name: | GDP-mannose 4,6-dehydratase | 
| Synonyms: | GMD; SDR3E1 | 
| Swissprot: | O60547 | 
| Gene Accession: | BC000117 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020). | 
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