中文名称:EIF2B3 抗原(重组蛋白)
英文名称: EIF2B3 Antigen (Recombinant Protein)
别 名: eukaryotic translation initiation factor 2B subunit gamma; EIF-2B; EIF2Bgamma
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to a region derived from 202-401 amino acids of human EIF2B3 | 
| Full name: | eukaryotic translation initiation factor 2B subunit gamma | 
| Synonyms: | EIF-2B; EIF2Bgamma | 
| Swissprot: | Q9NR50 | 
| Gene Accession: | BC018728 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | 
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