兔抗DHX38多克隆抗体

Background:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008]

Applications:

ELISA, IHC

Name of antibody:

DHX38

Immunogen:

Fusion protein of human DHX38

Full name:

DEAH-box helicase 38

Synonyms:

RP84; DDX38; PRP16; PRPF16

SwissProt:

Q92620

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer and Human esophagus cancer

IHC Recommend dilution:

100-300