中文名称:AP1S3抗原(重组蛋白)
英文名称: AP1S3 Antigen (Recombinant Protein)
别 名: PSORS15
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to a region derived from 1-104 amino acids of human AP1S3 | 
| Full name: | adaptor related protein complex 1 subunit sigma 3 | 
| Synonyms: | PSORS15 | 
| Swissprot: | Q96PC3 | 
| Gene Accession: | BC021898 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants. | 
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