POMGNT1 抗原（重组蛋白）

Full name:

protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)

Synonyms:

MEB; RP76; GNTI.2; LGMD2O; GnT I.2; MGAT1.2; gnT-I.2

Swissprot:

Q8WZA1

Gene Accession:

BC001471

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described.