中文名称: SUV39H1抗原(重组蛋白)
英文名称: SUV39H1 Antigen (Recombinant Protein)
别 名: MG44; KMT1A; SUV39H; H3-K9-HMTase 1
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to a region derived from 243-396 amino acids of human SUV39H1 | 
| Full name: | suppressor of variegation 3-9 homolog 1 | 
| Synonyms: | MG44; KMT1A; SUV39H; H3-K9-HMTase 1 | 
| Swissprot: | O43463 | 
| Gene Accession: | BC006238 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. | 
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