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021-54845833/15800441009
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Fusion protein corresponding to N terminal 300 amino acids of human RASAL1 |
Full name:
RAS protein activator like 1 (GAP1 like)
Synonyms:
RASAL
Swissprot:
O95294
Gene Accession:
BC014420
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation.
